If you have Steam Cloud enabled and there is a problem with your save games, this solution often resolves the issue.
How to resync save games
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Exit and re-open Steam
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Open Steam to the Game Library
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Right/Cmd click on Shadowrun: Dragonfall Director's Cut
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Click on “Properties”
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Select the “Updates” tab
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Make sure the "Enable Steam Cloud" checkbox is checked.
- Navigate to your Shadowrun: Dragonfall Director's Cut save game location (http://shadowrun-returns.wikispaces.com/Game+File+Locations+by+OS)
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Move all of your save game files OUT of the "...\remote\saves" folder and to a different folder (for backup purposes.)
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Fully quit and then restart Steam, and wait for Shadowrun: Dragonfall Director's Cut to finish syncing. This should re-sync all of your save game files from Steam cloud.
- Load your save game and then immediately use "Restart Level" from the PDA menu.